The Neuropathology Consortium is a collection of 60 brains, consisting of 15 each diagnosed with schizophrenia, bipolar disorder, or major depression, and unaffected controls. The four groups are matched by age, sex, race, postmortem interval, pH, side of brain, and mRNA quality as summarized in the
Demographic Details Chart.
Coded specimens are sent to researchers with the code varying from researcher to researcher to ensure that all studies are blinded. The code is released to the researcher only when the data have been collected and submitted to SMRI.
Further information about tissue availability, conditions for tissue use and how to request tissue is available of the SMRI homepage.
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The Stanley Neuropathology Consortium Integrative Database is a web based tool to integrate the SMRI data sets. Software is used to analyze correlations between neuropathology data and microarray expression profiles.
Data sets used in this database
Data sets for four different marker types from a total of 12 different brain regions
were included in this integrative database. Microarray expression data (hgu133a chips)
from prefrontal cortex and cerebellum are also included.
Tutorial
Citation
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